We are often recruiting for various phase 1 HIV vaccine and antibody infusion studies, which are a critical part of the pathway to finding an effective vaccine against HIV. These studies involve a small number of people who have lower risk of HIV infection based on their sexual activities or use of PrEP. The main purpose of phase 1 studies is to test the safety of the product, and to see if it causes an immune response.

Participation in a phase 1 study are specific to each study but might include:

• Giving urine, blood, and/or other samples.
• Receiving an investigational vaccine or antibody infusion.
• Visits to our clinic for 1-2 years.
• Keeping a diary for several days after injection or infusion visits.
• Regular contact with study clinicians.
• Regular physical exams.
• Answering questionnaires.

You may be eligible for a phase 1 study if you are:

• Between 18-50 years old, HIV negative, and in general good health.
• People who are taking PrEP may also be eligible for these studies.

Eligible participants will receive up to $125 per visit for their time and travel.

Send us a note using the form below and we’ll ring you back to see if you’re eligible for the study. It’s that simple!

Is a once a month PrEP pill possible? Help us find out.

Join a research study to test a new once-a-month PrEP pill. The study will test the safety of different doses, how the study medication works in the body, and potential side effects.

You may be eligible to participate if:

• HIV negative,
• 18-65 years old,
• and at low risk for HIV infection.

Eligible participants will receive up to $75-$300 per visit for their time & travel.

Send us a note using the form below and we’ll ring you back to see if you’re eligible for the study. It’s that simple!

The PrEPsmart study will test a mobile app designed to support people taking PrEP 2+1+1, which is also known as PrEP on demand.

Participants will be randomly assigned to receive the PrEPsmart app or usual support in taking PrEP.

Those receiving the app will be asked to download and use the PrEPsmart app over a 3-month period. All participants will complete online surveys and at home urine Tenofovir testing.

Enrolled participants may have the option to receive HIV/STI testing and PrEP from the study or continue through their current provider.

You may be eligible to participate if:

• You are 18 years or older,
• are HIV negative,
• are a cisgender man who has sex with other men,
• own a smartphone,
• and are interested in, or currently taking, PrEP 2+1+1 (PrEP on demand).

Eligible participants can receive between $175 to $375 for completing all study activities.

Send us a note using the form below and we’ll ring you back to see if you’re eligible for the study. It’s that simple!

The PrEP-3D study will pilot an online PrEP delivery service using Alto Pharmacy. Participation in the study involves downloading the Alto Pharmacy app to your phone and using their services to get your PrEP delivered to your home.

Participants must be willing to participate in the study for 3 to 6 months and complete home STI/HIV tests and online surveys. All study visits can take place online or remotely.

If eligible to participate, we will help you get PrEP. Some participants will also get access to the Alto Pharmacy app, which will allow them to get PrEP delivered to them.

You may be eligible to participate if:

• You are 18 years or older,
• are HIV negative,
• a cisgender man or transgender woman and have sex with men,
• are a California resident,
• own a smartphone,
• and are willing to get your PrEP delivered through Alto Pharmacy.

You will not be eligible If you are insured through Kaiser or health Plan of San Mateo.

Eligible participants can receive up to $250 to $600 if they complete all study procedures.

Send us a note using the form below and we’ll ring you back to see if you’re eligible for the study. It’s that simple!

Join a new study to help test a vaccine to prevent gonorrhea.

The purpose of the Gonorrhea Vaccine study is to learn if an FDA approved vaccine called Bexsero, which is used to prevent spinal meningitis (an infection of the lining of the brain and spinal cord) might also work in preventing gonorrhea. 

Study participation will include receiving shots in the arm (2 total, 2 months apart), giving blood samples, getting STI testing, and coming to our clinic for in-person visits (approximately 8 times over 16 months).

You may be eligible to participate if:

• You are 18-50 years old,
• sexually active,
• And are not a previous recipient of the Bexsero Meningitis B vaccine.

Eligible participants can receive $100-$175 per visit after screening.

Send us a note using the form below and we’ll ring you back to see if you’re eligible for the study. It’s that simple!

Active studies related to HIV cure science (including therapeutic vaccines) are conducted by our AIDS Clinical Trials Group (ACTG) partners at the Positive Health Program at the University of California, San Francisco.

Their studies range from strategies to address HIV-associated inflammation, innovative antiretroviral therapy treatment including regimen simplification / injectable medications, and optimization of treatment for complications related to co-infections. In addition, they have active research in tuberculosis and viral hepatitis (both hepatitis B and C) for people living with or without HIV.

For more information about actively enrolling studies, please call or text Dan Berrner at (415) 535-9495 or email him at daniel.berrner@ucsf.edu.